A spatial turn has occurred in various disciplines over the past decades. This article holds that it has not occurred in a similar decisive manner in theological discourse and not in South Africa in particular. After considering the necessity of a spatial turn and spatial consciousness, the article examines the concept of spatial justice against the backdrop of how injustice was and is spatially expressed in South African cities. Considering the way in which South African cities have evolved since the Native Land Act of 1913 – the segregated and apartheid city and the (post)apartheid city – the article then argues that deep and sustained reconciliation will be impossible should current spatial patterns of segregation, exclusion and injustice continue. It advocates theological and ecclesial participation in a national agenda for spatial transformation, to be fleshed out in relation to four interconnected challenges: land, landlessness, housing and home; the ‘creative destruction’ of neighbourhoods, gentrification and the displacement of the poor; participation in city-making (from below) and transformative spatial interventions; and close collaboration with social movements working for spatial justice. It concludes by asserting that such a trans- and/or post-disciplinary agenda for spatial justice would participate with the Spirit to mend the oikos of God.